ETD-Cleavable Linker for Confident Cross-linked Peptide Identifications
Sign Up to like & getrecommendations! Published in 2019 at "Journal of The American Society for Mass Spectrometry"
DOI: 10.1007/s13361-019-02227-1
Abstract: AbstractPeptide cross-links formed using the homobifunctional-linker diethyl suberthioimidate (DEST) are shown to be ETD-cleavable. DEST has a spacer arm consisting of a 6-carbon alkyl chain and it cleaves at the amidino groups created upon reaction… read more here.
Keywords: cross links; linker confident; cross; linker ... See more keywords
Evaluating the performance of an ETD-cleavable cross-linking strategy for elucidating protein structures.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2020.103846
Abstract: Chemical cross-linking is a powerful strategy for elucidating the structures of protein or protein complexes. The distance constraints obtained from cross-linked peptides represent the three-dimensional structures of the protein complexes. Unfortunately, structural analysis using cross-linking… read more here.
Keywords: cross; cross linker; cross linking; etd cleavable ... See more keywords