Mitoquinol improves phagocytosis and glycolysis in ethanol-exposed macrophages via HIF-1α-PFKP axis.
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DOI: 10.1093/jimmun/vkaf078
Abstract: Alcohol use disorder increases sepsis mortality. Acute ethanol exposure impairs pathogen clearance in the macrophages via dampened glycolysis and phagocytosis, exaggerates oxidative stress, and regulates the function of the hypoxia-regulating factor 1α (HIF-1α), a master… read more here.
Keywords: ethanol exposed; pfkp; ethanol; phagocytosis ... See more keywords