Minor Adaptations of Ethanol-Induced Release of Taurine Following Chronic Ethanol Intake in the Rat.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-94-024-1079-2_19
Abstract: Alcohol dependence is a puzzling brain disorder causing enormous suffering and financial costs world-wide. One of the few common denominators of all addictive drugs is activation of the mesolimbic dopamine system resulting in increased dopamine… read more here.
Keywords: minor adaptations; dopamine; ethanol intake; adaptations ethanol ... See more keywords
Effects of the hallucinogenic beverage ayahuasca on voluntary ethanol intake by rats and on cFos expression in brain areas relevant to drug addiction.
Sign Up to like & getrecommendations! Published in 2019 at "Alcohol"
DOI: 10.1016/j.alcohol.2019.10.005
Abstract: Ayahuasca is a hallucinogenic infusion used in religious ritualsthat has serotoninergic properties and may be a potential therapeutic option for drug addiction. In this study, Wistar rats had intermittent access to ethanol for 8 weeks,… read more here.
Keywords: ayahuasca; group; ethanol intake; cfos expression ... See more keywords
Mental nerve injury induces novelty seeking behaviour leading to increasing ethanol intake in Wistar rats.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2019.01.004
Abstract: OBJECTIVE Dental treatment and orofacial surgeries may induce chronic neuropathic orofacial pain (CNOP). This kind of pain affects adaptability to environmental changes in both model animals and humans. Part of the adaptation process depends on… read more here.
Keywords: seeking behaviour; ethanol intake; novelty seeking; novelty ... See more keywords
Differential effects of intra-ventral tegmental area ghrelin and glucagon-like peptide-1 on the stimulatory action of D-amphetamine and cocaine-induced ethanol intake in male Sprague Dawley rats
Sign Up to like & getrecommendations! Published in 2022 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2021.113726
Abstract: In order to further elucidate the role of mesolimbic peptides in the expression of ethanol reward, the present study investigated the effects of ghrelin and glucagon-like peptide-1 (GLP-1) on ethanol intake, in addition to ethanol… read more here.
Keywords: cocaine; ghrelin glucagon; amphetamine cocaine; ethanol intake ... See more keywords
Long-term effects of repeated maternal separation and ethanol intake on HPA axis responsiveness in adult rats
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DOI: 10.1016/j.brainres.2016.11.034
Abstract: It has been shown that early life manipulations produce behavioral, neural, and hormonal effects. The long term consequences of repeated maternal separation (RMS) plus cold stress and ethanol intake were evaluated during adolescence and adult… read more here.
Keywords: stress; ethanol intake; hpa axis; adult rats ... See more keywords
The selective κ-opioid receptor antagonist JDTic attenuates the alcohol deprivation effect in rats
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2019.10.003
Abstract: The mechanisms behind relapse to ethanol intake in recovering alcoholics are still unclear. The negative reinforcing effects contributing to ethanol addiction, including relapse, are considered to be partly driven by the κ-opioidergic system. As the… read more here.
Keywords: deprivation; alcohol deprivation; relapse; ethanol intake ... See more keywords
Activation of mitochondrial aldehyde dehydrogenase (ALDH2) by ALDA-1 reduces both the acquisition and maintenance of ethanol intake in rats: A dual mechanism?
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.12.001
Abstract: ABSTRACT A number of pre‐clinical studies have shown that brain‐generated acetaldehyde, the first metabolite of ethanol, exerts reinforcing effects that promote the acquisition of ethanol intake, while chronic intake maintenance appears to be mediated by… read more here.
Keywords: acquisition; ethanol intake; maintenance; aldh2 ... See more keywords
Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake
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DOI: 10.1016/j.neuropharm.2019.107917
Abstract: Prenatal ethanol exposure (PEE) promotes ethanol consumption in the adolescent offspring accompanied by the transcriptional regulation of kappa opioid receptor (KOR) system genes. This study analysed if environmental enrichment (EE, from gestational day 20 to… read more here.
Keywords: ethanol intake; ethanol; exposure; gene expression ... See more keywords
The offspring of rats selected for high or low ethanol intake at adolescence exhibit differential ethanol-induced Fos immunoreactivity in the central amygdala and in nucleus accumbens core
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2018.11.004
Abstract: ABSTRACT Adolescents exhibit, when compared to adults, altered responsivity to the unconditional effects of ethanol. It is unclear if this has a role in the excessive ethanol intake of adolescents. Wistar rats from the third… read more here.
Keywords: induced fos; adolescence; stdrlo; ethanol intake ... See more keywords
A history of ethanol intake accelerates the development of morphine analgesic tolerance: A protective potential for omega-3 fatty acids.
Sign Up to like & getrecommendations! Published in 2022 at "Behavioral neuroscience"
DOI: 10.1037/bne0000542
Abstract: Adolescence is a critical life period during which significant neurodevelopmental changes occur within the central nervous system. Consistently, substance abuse in this stage has been found to induce persistent changes in brain responsiveness to future… read more here.
Keywords: analgesic tolerance; ethanol intake; tolerance; morphine analgesic ... See more keywords
Voluntary Ethanol Intake Produces Subregion‐Specific Neuroadaptations in Striatal and Cortical Areas of Wistar Rats
Sign Up to like & getrecommendations! Published in 2019 at "Alcoholism: Clinical and Experimental Research"
DOI: 10.1111/acer.14014
Abstract: BACKGROUND Addiction has been conceptualized as a shift from controlled recreational use toward compulsive and habitual drug-taking behavior. Although the brain reward system is vital for alcohol reward and reinforcement, other neuronal circuits may be… read more here.
Keywords: produces subregion; voluntary ethanol; ethanol intake; wistar rats ... See more keywords