A comparison of three crystalline forms of miconazole: solvent-free, ethanol monosolvate and hemihydrate.
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DOI: 10.1107/s2053229622004909
Abstract: The crystal structures of miconazole {MIC, C18H14Cl4N2O, systematic name (RS)-1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole}, its ethanol monosolvate (C18H14Cl4N2O·C2H5OH) and its hemihydrate (C18H14Cl4N2O·0.5H2O) were compared. A detailed comparison of the molecular conformation of the miconazole molecules showed a structural similarity… read more here.
Keywords: ethanol monosolvate; comparison three; ethanol; hemihydrate ... See more keywords