Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy.
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DOI: 10.1007/s10565-021-09635-8
Abstract: Hepatocyte senescence is a key event participating in the progression of alcoholic liver disease. Autophagy is a critical biological process that controls cell fates by affecting cell behaviors like senescence. Pterostilbene is a natural compound… read more here.
Keywords: hepatocyte senescence; alcoholic liver; senescence; pterostilbene ... See more keywords