Synthesis, anticonvulsant screening, and molecular modeling studies of new arylalkylimidazole oxime ether derivatives
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DOI: 10.1002/ddr.21491
Abstract: In this study, 15 new oxime ether derivatives were synthesized and their anticonvulsant activities were screened in vivo. The compounds were synthesized by the reaction of various alkyl halides with 1‐(2‐naphthyl)‐2‐(1H‐imidazol‐1‐yl)ethanone oxime. Their anticonvulsant activities… read more here.
Keywords: oxime; anticonvulsant screening; oxime ether; synthesis anticonvulsant ... See more keywords
Two New Diphenyl Ether Derivatives from the Fermentation Products of an Endophytic Fungus Phomopsis fukushii
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DOI: 10.1007/s10600-019-02706-7
Abstract: Two new diphenyl ethers, 1-[2-methoxy-4-(3-methoxy-5-methylphenoxy)-6-methylphenyl]-ethanone (1) and 1-[4-(3-(hydroxymethyl)-5-methoxyphenoxy)-2-methoxy-6-methylphenyl]-ethanone (2), together five known diphenyl ether derivatives (3–7), were isolated from the fermentation products of an endophytic fungus Phomopsis fukushii. Their structures were elucidated by spectroscopic methods,… read more here.
Keywords: new diphenyl; two new; diphenyl; fermentation products ... See more keywords
Design, synthesis, biological evaluation and molecular docking of novel isatin-oxime ether derivatives as potential IDH1 inhibitors
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DOI: 10.1007/s11030-024-11084-4
Abstract: A series of novel isatin-oxime ether derivatives were designed, synthesized and characterized by 1H NMR and 13C NMR and HRMS. These compounds were evaluated for their in vitro cytotoxicity against three human cancer cell lines… read more here.
Keywords: molecular docking; ether derivatives; oxime ether; isatin oxime ... See more keywords
Diphenyl Ether Derivatives as Potential Liquid Organic Hydrogen Carriers: Thermochemical and Computational Study
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DOI: 10.1021/acs.jced.9b00502
Abstract: The liquid organic hydrogen carriers (LOHCs) are promising materials for hydrogen storage. The standard molar enthalpies of formation, ΔfHmo(liq/cr) of diphenyl ether substituted with methyl, methoxy, and hydroxyl substituents were measured by the high-precision combustion… read more here.
Keywords: liquid organic; organic hydrogen; ether derivatives; hydrogen carriers ... See more keywords
Anticancer Activity of Ether Derivatives of Chrysin
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DOI: 10.3390/molecules30040960
Abstract: Chrysin, a naturally occurring flavonoid, exhibits a broad spectrum of biological activities, including showing anticancer properties. However, its clinical application is limited by poor bioavailability and low solubility. The introduction of an amine, amide, ester,… read more here.
Keywords: ether derivatives; activity ether; anticancer activity; derivatives chrysin ... See more keywords