Oxime Ether Lipids as Transfection Agents: Assembly and Complexation with siRNA.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7138-1_16
Abstract: RNAi-based therapeutic approaches to combat cancer and other diseases are currently an area of great interest. However, practical applications of this approach rely on optimal tools to carry and deliver siRNA to the desired site.… read more here.
Keywords: ether lipids; oxime ether; sirna delivery; lipids transfection ... See more keywords
Differential Sensitivity of pHLIP to Ester and Ether Lipids.
Sign Up to like & getrecommendations! Published in 2019 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2019.104849
Abstract: pH (low) insertion peptide (pHLIP) is a polypeptide from the third transmembrane helix of bacteriorhodopsin. The pH-dependent membrane insertion of pHLIP has been conveniently exploited for translocation of cargo molecules and as a novel imaging… read more here.
Keywords: ester ether; ether lipids; phlip; ester ... See more keywords
Structural Characterization and Quantitation of Ether-Linked Glycerophospholipids in Peroxisome Biogenesis Disorder Tissue by Ultraviolet Photodissociation Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01274
Abstract: The biological impact of ether glycerophospholipids (GP) in peroxisomal disorders and other diseases makes them significant targets as biomarkers for diagnostic assays or deciphering pathology of the disorders. Ether lipids include both plasmanyl and plasmenyl… read more here.
Keywords: mass spectrometry; ether lipids; characterization; tissue ... See more keywords
The origins and implications of glycerol ether lipids in China coastal wetland sediments
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-55104-y
Abstract: Coastal wetlands are terrestrial-marine transition zones harboring diverse active microbial communities. The origins of diverse glycerol ether lipids preserved in coastal wetlands are rarely investigated. 16 surface sediments were collected from the coastal wetland at… read more here.
Keywords: ether lipids; glycerol ether; gdgts; coastal wetland ... See more keywords
Roles of endogenous ether lipids and associated PUFAs in the regulation of ion channels and their relevance for disease.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of lipid research"
DOI: 10.1194/jlr.ra120000634
Abstract: Ether lipids (ELs) are lipids characterized by the presence of either an ether linkage (alkyl lipids) or a vinyl ether linkage [i.e., plasmalogens (Pls)] at the sn1 position of the glycerol backbone, and they are… read more here.
Keywords: ether lipids; ion channels; ion; disease ... See more keywords
Ether Lipids in Obesity: From Cells to Population Studies
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.841278
Abstract: Ether lipids are a unique class of glycero- and glycerophospho-lipid that carry an ether or vinyl ether linked fatty alcohol at the sn-1 position of the glycerol backbone. These specialised lipids are important endogenous anti-oxidants… read more here.
Keywords: obesity; lipids obesity; population studies; ether lipids ... See more keywords
Ether Lipid-Mediated Antioxidant Defense in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020293
Abstract: One of the richest tissues in lipid content and diversity of the human body is the brain. The human brain is constitutively highly vulnerable to oxidative stress. This oxidative stress is a determinant in brain… read more here.
Keywords: alzheimer disease; brain; antioxidant defense; human brain ... See more keywords
Overlapping and Distinct Features of Cardiac Pathology in Inherited Human and Murine Ether Lipid Deficiency
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24031884
Abstract: Inherited deficiency in ether lipids, a subgroup of glycerophospholipids with unique biochemical and biophysical properties, evokes severe symptoms in humans resulting in a multi-organ syndrome. Mouse models with defects in ether lipid biosynthesis have widely… read more here.
Keywords: lipid deficient; pathology; lipid deficiency; ether lipids ... See more keywords