Ethnic-specific BRCA1/2 variation within Asia population: evidence from over 78 000 cancer and 40 000 non-cancer cases of Indian, Chinese, Korean and Japanese populations
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Genetics"
DOI: 10.1136/jmedgenet-2020-107299
Abstract: Background Germline mutation in BRCA1 and BRCA2 (BRCA) is genetic predisposition for breast and ovarian cancer. Identification of mutation carriers is a critical step to prevent and treat the cancer in the mutation carriers. Human… read more here.
Keywords: brca variation; variation; cancer; population ... See more keywords
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci
Sign Up to like & getrecommendations! Published in 2021 at "Genome Medicine"
DOI: 10.1186/s13073-021-00877-z
Abstract: Background DNA methylation (DNAm) is associated with gene regulation and estimated glomerular filtration rate (eGFR), a measure of kidney function. Decreased eGFR is more common among US Hispanics and African Americans. The causes for this… read more here.
Keywords: kidney; ethnic ethnic; trans ethnic; kidney function ... See more keywords
Metabolic drivers of dysglycemia in pregnancy: ethnic-specific GWAS of 146 metabolites and 1-sample Mendelian randomization analyses in a UK multi-ethnic birth cohort
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1157416
Abstract: Introduction Gestational diabetes mellitus (GDM) is the most common pregnancy complication worldwide and is associated with short- and long-term health implications for both mother and child. Prevalence of GDM varies between ethnicities, with South Asians… read more here.
Keywords: sample mendelian; ethnic specific; pregnancy; cohort ... See more keywords