Variations in the frequencies of polymorphisms in the CYP2C9 gene in six major ethnicities of Pakistan
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DOI: 10.1038/s41598-020-76366-x
Abstract: Genetic variation in cytochrome P450 (CYP) 2C9 is known to cause significant inter-individual differences in drug response and adverse effects. The frequencies of CYP2C9*2 and CYP2C9*3, both of which are responsible for the low activity… read more here.
Keywords: low activity; major ethnicities; ethnicities pakistan; activity ... See more keywords
Estimation of polymorphisms in the drug-metabolizing enzyme, cytochrome P450 2C19 gene in six major ethnicities of Pakistan.
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DOI: 10.1080/21655979.2021.1955809
Abstract: Interindividual differences in cytochrome P450 (CYP) 2C19 activity may result in variations in the therapeutic response to drugs metabolized by this enzyme. Differences at gene level may translate into protein level with consequent impairment of… read more here.
Keywords: ethnicities pakistan; frequency; genotype; cytochrome p450 ... See more keywords