Continuous-Flow Microreactor for Knoevenagel Condensation of Ethyl Cyanoacetate with Benzaldehyde: Effect of Grafted Amino Groups on Catalytic Activity.
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DOI: 10.1002/cplu.202200390
Abstract: Ethyl α-cyanocinnamate was synthesized in the Knoevenagel condensation of benzaldehyde and ethyl cyanoacetate in flow monolithic microreactor of 0.63 cm3 volume. The catalytically active core was made of silica monolith modified with various amine group… read more here.
Keywords: knoevenagel condensation; ethyl cyanoacetate; catalytic activity; activity ... See more keywords
Unexpected Aldehyde-Catalyzed Reaction of Imidazole N-Oxides with Ethyl Cyanoacetate
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DOI: 10.1055/s-0039-1691527
Abstract: The reaction of 2-unsubstituted imidazole N-oxides with ethyl cyanoacetate and aromatic aldehydes leads to the formation of ethyl 2-cyano-2-(1,3-dihydro-2H-imidazole-2-ylidene)acetates. The reaction proceeds through an initial [3+2] cycloaddition, followed by cleavage of the cycloadduct and regeneration… read more here.
Keywords: ethyl cyanoacetate; aldehyde catalyzed; unexpected aldehyde; imidazole oxides ... See more keywords