Crystal structures of (E)-4-[1-(2-carbamothioylhydrazinylidene)ethyl]phenyl acetate and (E)-4-[1-(2-carbamothioylhydrazinylidene)ethyl]phenyl benzoate
Sign Up to like & getrecommendations! Published in 2017 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989016018983
Abstract: In the title compounds, the thiosemicarbazone group adopts an extended conformation, and there is a short N—H⋯N contact present forming an S(5) ring motif. In the crystals of both compounds, molecules are linked by pairs… read more here.
Keywords: structures carbamothioylhydrazinylidene; crystal structures; carbamothioylhydrazinylidene ethyl; phenyl acetate ... See more keywords
(E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27227719
Abstract: (E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide (compound 10) was designed as an antiangiogenic VEGFR-2 inhibitor with the essential pharmacophoric structural properties to interact with the catalytic pocket of VEGFR-2. The designed derivative was synthesized, and its structure was confirmed through… read more here.
Keywords: phenyl nicotinamide; pyridine derivative; benzoyl hydrazono; ethyl phenyl ... See more keywords