In vitro and in silico hormonal activity studies of di‐(2‐ethylhexyl)terephthalate, a di‐(2‐ethylhexyl)phthalate substitute used in medical devices, and its metabolites
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3792
Abstract: Plasticizers added to polyvinylchloride used in medical devices can be released into patients’ biological fluids. The substitution of di‐(2‐ethylhexyl)phthalate (DEHP) by alternative plasticizers is essential but their safety must be demonstrated. DEHP, di‐(2‐ethylhexyl)terephthalate (DEHT) and… read more here.
Keywords: used medical; ethylhexyl terephthalate; ethylhexyl phthalate; medical devices ... See more keywords
Reproductive toxicity of maternal exposure to di(2‐ethylhexyl)phthalate and butyl paraben (alone or in association) on both male and female Wistar offspring
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4377
Abstract: Parabens and phthalates are commonly found as contaminants in human fluids and are able to provoke reproductive toxicity, being considered endocrine disruptors. To evaluate the effects of phthalate and paraben, alone or in combination, on… read more here.
Keywords: paraben alone; ethylhexyl phthalate; phthalate; toxicity ... See more keywords
Maternal rodent exposure to di‐(2‐ethylhexyl) phthalate decreases muscle mass in the offspring by increasing myostatin
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13098
Abstract: Di‐(2‐ethylhexyl) phthalate (DEHP) and its metabolites can cross the placenta and may cause birth defects and developmental disorders. However, whether maternal DEHP exposure affects skeletal muscle development in the offspring and the pathways involved are… read more here.
Keywords: ethylhexyl phthalate; exposure ethylhexyl; rodent exposure; maternal rodent ... See more keywords
Di(2‐ethylhexyl) phthalate induced thyroid toxicity via endoplasmic reticulum stress: In vivo and in vitro study
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23648
Abstract: Di(2‐ethylhexyl) phthalate (DEHP) could induce thyroid injury but the mechanism was unclear. This study combined in vivo and in vitro experiments to clarify the mechanism. In vivo, the offspring of Sprague Dawley rats were gavaged… read more here.
Keywords: vitro; stress; ethylhexyl phthalate; toxicity ... See more keywords
Di(2‐ethylhexyl) phthalate and microplastics cause necroptosis and apoptosis in hepatocytes of mice by inducing oxidative stress
Sign Up to like & getrecommendations! Published in 2023 at "Environmental Toxicology"
DOI: 10.1002/tox.23759
Abstract: Di(2‐ethylhexyl) phthalate (DEHP) is a plasticizer and an endocrine disruptor. Microplastics (MPs) are pathogenic small plastic particles and abundant in the aqueous environment. The problem of residual hazards of plastic products is worthy of study,… read more here.
Keywords: ethylhexyl phthalate; dehp mps; oxidative stress; plastic ... See more keywords
Protective effect of Lycium barbarum polysaccharide on di-(2-ethylhexyl) phthalate-induced toxicity in rat liver
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-020-11990-8
Abstract: Di-(2-ethylhexyl)-phthalate (DEHP) is the most commonly used plasticizer and it has been a ubiquitous environmental contaminant which affects health. The purpose of this study was to investigate the protective effect of the Lycium barbarum polysaccharide… read more here.
Keywords: toxicity rat; protective effect; barbarum polysaccharide; ethylhexyl phthalate ... See more keywords
Effect of di(2-ethylhexyl) phthalate on Nrf2-regulated glutathione homeostasis in mouse kidney
Sign Up to like & getrecommendations! Published in 2020 at "Cell Stress and Chaperones"
DOI: 10.1007/s12192-020-01127-8
Abstract: Environmental toxicants such as phthalate have been involved in multiple health disorders including renal diseases. Oxidative damage is implicated in many alterations caused by phthalate especially the di(2-ethylhexyl) phthalate (DEHP), which is the most useful… read more here.
Keywords: protein; phthalate; nrf2; ethylhexyl phthalate ... See more keywords
Remediation of soil contaminated by di(2-ethylhexyl) phthalate by chemical oxidation or bioremediation
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Environmental Science and Technology"
DOI: 10.1007/s13762-020-03007-1
Abstract: Soil leachates from di(2-ethylhexyl)phthalate-contaminated soil to groundwater could potentially cause toxicity, depending on the physical and chemical properties of the soil, and modifications in the phthalate, thus affecting health in nearby human populations. For this… read more here.
Keywords: remediation; toxicity; chemical oxidation; soil ... See more keywords
Response of Trichogramma papilionis to semiochemicals induced by host oviposition on plants
Sign Up to like & getrecommendations! Published in 2020 at "Biological Control"
DOI: 10.1016/j.biocontrol.2020.104510
Abstract: Abstract Parasitoid wasps may rely on chemical volatiles from herbivorous insects and their plant hosts for finding their preferred host. This study was conducted to test the reaction of Trichogramma papilionis Nagarkatti (Hymenoptera: Trichogrammatidae) to… read more here.
Keywords: bis ethylhexyl; papilionis; ethylhexyl phthalate; trichogramma papilionis ... See more keywords
Systematic review and meta-analysis of early life exposure to di(2-ethylhexyl) phthalate and obesity related outcomes in rodents.
Sign Up to like & getrecommendations! Published in 2017 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.08.165
Abstract: BACKGROUND It has been suggested that the plasticizer di(2-ethylhexyl) phthalate (DEHP) exerts obesogenic effects after pre- or perinatal exposure. OBJECTIVE A systematic review with meta-analyses was conducted of early life exposure to DEHP, or its… read more here.
Keywords: exposure; early life; life exposure; meta ... See more keywords
Embryonic exposure to Mono(2-ethylhexyl) phthalate (MEHP) disrupts pancreatic organogenesis in zebrafish (Danio rerio).
Sign Up to like & getrecommendations! Published in 2018 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2017.12.094
Abstract: Mono(2-ethylhexyl) phthalate (MEHP) is the bioactive metabolite of di(2-ethylhexyl) phthalate, a plasticizing agent and persistent environmental contaminant associated with obesity, developmental abnormalities, and oxidative stress. Nrf2 (Nfe2l2) is a transcription factor that regulates cytoprotective genes… read more here.
Keywords: mehp; ethylhexyl phthalate; mehp exposure; exposure ... See more keywords