A Genetic Screen Identifies Etl4-Deficiency Capable of Stabilizing the Haploidy in Embryonic Stem Cells
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DOI: 10.1016/j.stemcr.2020.11.016
Abstract: Summary Mammalian haploid embryonic stem cells (haESCs) hold great promise for functional genetic studies and forward screening. However, all established haploid cells are prone to spontaneous diploidization during long-term culture, rendering application challenging. Here, we… read more here.
Keywords: embryonic stem; diploidization; etl4 deficiency; stem ... See more keywords