The inhibition of GHR enhanced cytotoxic effects of etoposide on neuroblastoma.
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DOI: 10.1016/j.cellsig.2021.110081
Abstract: Etoposide, a DNA damage-inducing agent, is widely used to treat neuroblastoma. Etoposide binds to and inhibits topoisomerase II, thereby inducing the DNA damage response. However, the underlying mechanism of etoposide resistance in neuroblastoma remains unclear.… read more here.
Keywords: cell viability; effects etoposide; etoposide resistance; neuroblastoma ... See more keywords