Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Cell metabolism"
DOI: 10.1016/j.cmet.2020.10.022
Abstract: Effector regulatory T (eTreg) cells are essential for immune tolerance and depend upon TÂ cell receptor (TCR) signals for generation. The immunometabolic signaling mechanisms that promote the differentiation and maintenance of eTreg cells remain unclear. Here,… read more here.
Keywords: treg; etreg; differentiation maintenance; differentiation ... See more keywords
Abstract 2702: Contribution of effector regulatory T cells to the regulation of antitumor immunity
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DOI: 10.1158/1538-7445.am2019-2702
Abstract: Regulatory T cells (Treg) belonging to the FoxP3 lineage stringently control immune responses and self-tolerance. Follicular regulatory T (TFR) cells, an effector Treg (eTreg) subset, not only suppress cellular responses but also regulate the magnitude… read more here.
Keywords: antitumor immunity; effector; blimp1; etreg ... See more keywords