RegEnrich gene regulator enrichment analysis reveals a key role of the ETS transcription factor family in interferon signaling
Sign Up to like & getrecommendations! Published in 2022 at "Communications Biology"
DOI: 10.1038/s42003-021-02991-5
Abstract: Changes in a few key transcriptional regulators can lead to different biological states. Extracting the key gene regulators governing a biological state allows us to gain mechanistic insights. Most current tools perform pathway/GO enrichment analysis… read more here.
Keywords: analysis; expression; enrichment analysis; ets transcription ... See more keywords
p53 Loss Mediates Hypersensitivity to ETS Transcription Factor Inhibition Based on PARylation-Mediated Cell Death Induction
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DOI: 10.3390/cancers12113205
Abstract: Simple Summary ETS transcription factors are potent oncogenic drivers in several cancer types and represent promising therapeutic targets. However, molecular factors influencing response to ETS factor inhibition are widely unknown so far. Here, we uncover… read more here.
Keywords: inhibition; ets transcription; cell death; p53 ... See more keywords