ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes
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DOI: 10.1172/jci.insight.140332
Abstract: ETV6 is an ETS family transcription factor that plays a key role in hematopoiesis and megakaryocyte development. Our group and others have identified germline mutations in ETV6 resulting in autosomal dominant thrombocytopenia and predisposition to… read more here.
Keywords: etv6 germline; interferon response; hdac3 ncor2; response genes ... See more keywords