The crystal structure of Pyrococcus furiosus RecJ implicates it as an ancestor of eukaryotic Cdc45.
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.2210/pdb5x4j/pdb
Abstract: RecJ nucleases specifically degrade single-stranded (ss) DNA in the 5' to 3' direction. Archaeal RecJ is different from bacterial RecJ in sequence, domain organization, and substrate specificity. The RecJ from archaea Pyrococcus furiosus (PfuRecJ) also… read more here.
Keywords: crystal structure; eukaryotic cdc45; pyrococcus furiosus; domain ... See more keywords