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   Articles with "eukaryotic translation" as a keyword



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The role of eukaryotic translation initiation factor 5A-1 (eIF5A-1) gene in HPV 16 E6 induces cell growth in human cervical squamous carcinoma cells.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.08.018

Abstract: Human Papillomavirus (HPV) is considered as the major risk factor for the development and progression of cervical cancer. The high expression of HPV 16 E6 may be the causative factor for induction and maintenance of… read more here.

Keywords: carcinoma; initiation factor; hpv; factor ... See more keywords
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Upregulation of eukaryotic translation initiation factor 3 subunit a promotes cell survival in ameloblastoma.

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recommendations! Published in 2019 at "Oral surgery, oral medicine, oral pathology and oral radiology"

DOI: 10.1016/j.oooo.2019.02.016

Abstract: OBJECTIVES This study aimed to detect the expression of eukaryotic translation initiation factor 3 subunit a (eIF3a) in ameloblastoma (AB) tissues compared with normal oral mucosa (NOM) tissues and investigate the roles of eIF3a in… read more here.

Keywords: eukaryotic translation; ameloblastoma; translation initiation; factor subunit ... See more keywords
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Eukaryotic translation elongation factor 1δ, N-terminal propeptide of type I collagen and cancer-associated fibroblasts are prognostic markers of oral squamous cell carcinoma patients.

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recommendations! Published in 2020 at "Oral surgery, oral medicine, oral pathology and oral radiology"

DOI: 10.1016/j.oooo.2020.09.003

Abstract: OBJECTIVE Identifying markers that influence oral squamous cell carcinoma (OSCC) prognosis is a fundamental strategy to improve the overall survival of patients. Markers such as eukaryotic translation elongation factor 1δ (EEF1D), fascin, N-terminal propeptide of… read more here.

Keywords: translation elongation; cell carcinoma; oral squamous; elongation factor ... See more keywords
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Major structural rearrangements of the canonical eukaryotic translation initiation complex.

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recommendations! Published in 2018 at "Current opinion in structural biology"

DOI: 10.1016/j.sbi.2018.08.006

Abstract: Translation initiation in eukaryotes is a complex multistep process that requires the interplay of over a dozen protein factors together with the small ribosomal subunit (SSU) and the mRNA. During all these steps, the SSU… read more here.

Keywords: process; translation; biology; eukaryotic translation ... See more keywords
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Clinical significance of eukaryotic translation initiation factor 5A2 in papillary thyroid cancer

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recommendations! Published in 2020 at "Bioengineered"

DOI: 10.1080/21655979.2020.1848753

Abstract: ABSTRACT Eukaryotic translation initiation factor 5A2 (eIF5A2) plays an important role in tumor progression and prognosis evaluation. However, the potential role of eIF5A2 in human papillary thyroid cancer (PTC) is unknown. In this study, we… read more here.

Keywords: eif5a2; factor 5a2; initiation factor; ptc ... See more keywords
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Overexpression of Eukaryotic translation initiation factor 3D induces stem cell-like properties and metastasis in cervix cancer by activating FAK through inhibiting degradation of GRP78

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recommendations! Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2021.2024336

Abstract: ABSTRACT Cervix cancer (CC) is the most common gynecological malignancy and the leading cause of morbidity among women worldwide. Previous study indicated that cancer stem cells (CSCs) existed in cervix cancer, and suppressing CSC characteristics… read more here.

Keywords: cervix cancer; eukaryotic translation; translation initiation; cancer ... See more keywords

Extensions, Extra Factors, and Extreme Complexity: Ribosomal Structures Provide Insights into Eukaryotic Translation.

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recommendations! Published in 2019 at "Cold Spring Harbor perspectives in biology"

DOI: 10.1101/cshperspect.a032367

Abstract: SUMMARYAlthough the basic aspects of protein synthesis are preserved in all kingdoms of life, there are many important structural and functional differences between bacterial and the more complex eukaryotic ribosomes. High-resolution cryo-electron microscopy (cryo-EM) and… read more here.

Keywords: eukaryotic ribosomes; insights eukaryotic; translation; biology ... See more keywords
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The eukaryotic translation elongation factor 1A regulation of actin stress fibers is important for infectious RSV production

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recommendations! Published in 2018 at "Virology Journal"

DOI: 10.1186/s12985-018-1091-7

Abstract: Cellular protein eukaryotic translation elongation factor 1A (eEF1A) is an actin binding protein that plays a role in the formation of filamentous actin (F-actin) bundles. F-Actin regulates multiple stages of respiratory syncytial virus (RSV) replication… read more here.

Keywords: translation elongation; actin; formation; rsv ... See more keywords

Interplay between reversible phosphorylation and irreversible ADP-ribosylation of eukaryotic translation elongation factor 2

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recommendations! Published in 2019 at "Biological Chemistry"

DOI: 10.1515/hsz-2018-0280

Abstract: Abstract The functionality of eukaryotic translation elongation factor 2 (eEF2) is modulated by phosphorylation, eEF2 is simultaneously the molecular target of ADP-ribosylating toxins. We analyzed the interplay between phosphorylation and diphthamide-dependent ADP-ribosylation. Phosphorylation does not… read more here.

Keywords: phosphorylation; eukaryotic translation; s595; adp ribosylation ... See more keywords
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Eukaryotic translation initiation factor 3 subunit G (EIF3G) resensitized HCT116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1

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recommendations! Published in 2018 at "OncoTargets and therapy"

DOI: 10.2147/ott.s170854

Abstract: Purpose Colorectal cancer (CRC) has become a predominant cancer and accounts for approximately 10% of cancer-related mortality. Drug resistance still remains a priority mortality factor for patients due to no available therapeutic alternatives. The purpose… read more here.

Keywords: initiation factor; factor; eif3g resensitized; eukaryotic translation ... See more keywords

The Role of the Eukaryotic Translation Initiation Factor 4E (eIF4E) in Neuropsychiatric Disorders

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recommendations! Published in 2018 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2018.00561

Abstract: Protein synthesis in eukaryotic cells is a complex, multi-step and tightly regulated process. Translation initiation, the rate limiting step in protein synthesis, is dependent on the activity of eukaryotic translation Initiation Factor 4E (eIF4E). eIF4E… read more here.

Keywords: initiation; factor eif4e; initiation factor; eukaryotic translation ... See more keywords