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   Articles with "eupatilin" as a keyword



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Eupatilin alleviates inflammatory response after subarachnoid hemorrhage by inhibition of TLR4/MyD88/NF‐κB axis

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recommendations! Published in 2023 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23317

Abstract: Early brain injury (EBI) is associated with the adverse prognosis of subarachnoid hemorrhage (SAH) patients. The key bioactive component of the Chinese herbal medicine Artemisia asiatica Nakai (Asteraceae) is eupatilin. Recent research reports that eupatilin… read more here.

Keywords: subarachnoid hemorrhage; brain; eupatilin; tlr4 myd88 ... See more keywords
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Eupatilin Ameliorates Cerulein-Induced Pancreatitis Via Inhibition of the Protein Kinase D1 Signaling Pathway In Vitro.

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recommendations! Published in 2020 at "Pancreas"

DOI: 10.1097/mpa.0000000000001488

Abstract: OBJECTIVE The aim of this study was to investigate the effects of eupatilin on protein kinase D1 (PKD1) and nuclear factor kappa B (NF-κB) signaling pathways in cerulein-induced in vitro pancreatitis. METHODS We used collagenase… read more here.

Keywords: pancreatitis; cerulein induced; eupatilin; protein kinase ... See more keywords

Novel Application of Eupatilin for Effectively Attenuating Cisplatin-Induced Auditory Hair Cell Death via Mitochondrial Apoptosis Pathway

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/1090034

Abstract: Eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone) is a pharmacologically active flavone that has been isolated from a variety of medicinal plants and possesses a number of pharmacological properties. This study evaluates the antioxidant and antiapoptotic effects of eupatilin on… read more here.

Keywords: hair cell; apoptosis; hair; cisplatin induced ... See more keywords

Eupatilin exerts neuroprotective effects in mice with transient focal cerebral ischemia by reducing microglial activation

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0171479

Abstract: Microglial activation and its-driven neuroinflammation are characteristic pathogenetic features of neurodiseases, including focal cerebral ischemia. The Artemisia asiatica (Asteraceae) extract and its active component, eupatilin, are well-known to reduce inflammatory responses. But the therapeutic potential… read more here.

Keywords: focal cerebral; eupatilin; cerebral ischemia; microglial activation ... See more keywords

Pretreatment with Eupatilin Attenuates Inflammation and Coagulation in Sepsis by Suppressing JAK2/STAT3 Signaling Pathway

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recommendations! Published in 2023 at "Journal of Inflammation Research"

DOI: 10.2147/jir.s393850

Abstract: Purpose Sepsis is an aggressive and life-threatening organ dysfunction induced by infection. Excessive inflammation and coagulation contribute to the negative outcomes for sepsis, resulting in high morbidity and mortality. In this study, we explored whether… read more here.

Keywords: sepsis; coagulation; jak2 stat3; group ... See more keywords