Euphorbia tirucalli β‐Amyrin Synthase: Critical Roles of Steric Sizes at Val483 and Met729 and the CH–π Interaction between Val483 and Trp534 for Catalytic Action
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DOI: 10.1002/cbic.201700368
Abstract: The functions of Val483, Trp534, and Met729 in Euphorbia tirucalli β‐amyrin synthase were revealed by comparing the enzyme activities of site‐directed mutants against that of the wild type. The Gly and Ala variants with a… read more here.
Keywords: amyrin synthase; val483 trp534; tirucalli amyrin; bulk ... See more keywords
The latex of Euphorbia tirucalli inhibits staphyloxanthin production and protects Tenebrio molitor larvae against Staphylococcus aureus infection
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DOI: 10.1080/14786419.2019.1582036
Abstract: Abstract The latex of Euphorbia tirucalli L. (LET) has great etnopharmacological relevance for several traditional communities. In this study, the in vitro and in vivo (using Tenebrio molitor larvae) antimicrobial effects of LET were evaluated.… read more here.
Keywords: molitor larvae; tenebrio molitor; latex euphorbia; euphorbia tirucalli ... See more keywords
Euphorbia tirucalli latex loaded polymer nanoparticles: Synthesis, characterization, in vitro release and in vivo antinociceptive action
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DOI: 10.1371/journal.pone.0274432
Abstract: The encapsulation of drugs in micro and nanocarriers has helped to resolve mechanisms of cellular resistance and decrease drug side effects as well. In this study, poly(D,L-lactide-co-glycolide) (PLGA) was used to encapsulate the Euphol active… read more here.
Keywords: latex; euphorbia tirucalli; technique used; release ... See more keywords
Antiproliferative activity of extracts of Euphorbia tirucalli L (Euphorbiaceae) from three regions of Brazil
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DOI: 10.4314/tjpr.v16i5.7
Abstract: Purpose: To investigate Euphorbia tirucalli extract for probable geographic variations in its antiproliferative activity. Methods: The aerial parts of E. tirucalli were collected in the Brazilian states of Mato Grosso, Rio de Janeiro, Para, Minas… read more here.
Keywords: activity extracts; tirucalli euphorbiaceae; antiproliferative activity; euphorbia tirucalli ... See more keywords