The conect4children (c4c) Consortium: Potential for Improving European Clinical Research into Medicines for Children
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutical Medicine"
DOI: 10.1007/s40290-020-00373-6
Abstract: The need for information about new and existing drugs used in children was recognized in the European Union (EU) with the implementation of the Paediatric Regulation in 2007. In 2017, the 10-year review of the… read more here.
Keywords: conect4children c4c; consortium; network; clinical research ... See more keywords
Study factors associated with the incompletion of clinical trials that include pediatric patients: a retrospective analysis of the European Clinical Trials Database and a lesson from the European region
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DOI: 10.1186/s13063-021-05143-6
Abstract: Background Incomplete clinical trials for pediatric drug development result in a lack of adequate scientific evidence for providing appropriate medication to pediatric populations; this is especially true for Japan. Thus, using the European Clinical Trials… read more here.
Keywords: analysis; cases completed; clinical trials; trials database ... See more keywords
A Multicentric European Clinical Study on Custom-Made Porous Hydroxyapatite Cranioplasty in a Pediatric Population
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DOI: 10.3389/fsurg.2022.848620
Abstract: Background Cranioplasty (CP) is a surgical intervention aiming to re-establish the integrity of skull defects. Autologous bone and different heterologous materials are used for this purpose, with various reported related complications, especially in children.This study… read more here.
Keywords: european clinical; porous hydroxyapatite; multicentric european; group ... See more keywords
Dirofilaria immitis: Genotyping Randomly Selected European Clinical Samples and USA Laboratory Isolates with Molecular Markers Associated with Macrocyclic Lactone Susceptibility and Resistance
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DOI: 10.3390/pathogens11080934
Abstract: Dirofilaria immitis is a parasitic nematode and causes dirofilariosis, a potentially fatal pulmonary infection which primarily infects canids. Dirofilariosis infections are controlled via prophylactic macrocyclic lactone (ML) regimens. Recent evidence has confirmed the development of… read more here.
Keywords: european clinical; dirofilaria immitis; resistance; usa laboratory ... See more keywords