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Published in 2021 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2021.03.004
Abstract: The number and distribution of recessive alleles in the population for various diseases are not known at genome-wide-scale. Based on 6,447 exome sequences of healthy, genetically unrelated Europeans of two distinct ancestries, we estimate that…
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Keywords:
variants european;
pathogenic variants;
autosomal recessive;
european populations ... See more keywords
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Published in 2017 at "Annals of Human Biology"
DOI: 10.1080/03014460.2017.1346708
Abstract: Abstract Background: The ε2, ε3 and ε4 alleles of APOE gene have been associated with several diseases in different populations. Data on the frequency of alleles are used in both a clinical and evolutionary context.…
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Keywords:
frequency alleles;
study apoe;
frequency;
european populations ... See more keywords
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Published in 2020 at "Journal of Fish Biology"
DOI: 10.1111/jfb.14448
Abstract: The tench Tinca tinca is a freshwater species with human-mediated translocations, aquaculture interest and limited information on its genetic structure. mtDNA sequencing analysis of control region and two genes in 50 individuals from five European…
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Keywords:
european populations;
tinca tinca;
genetic structure;
tinca ... See more keywords
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Published in 2021 at "Plant biology"
DOI: 10.1111/plb.13332
Abstract: Local adaptation and the evolution of phenotypic plasticity may facilitate biological invasions. Both processes can enhance germination and seedling recruitment, which are crucial life-history traits for plants. The rate, timing and speed of germination have…
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Keywords:
germination;
locust robinia;
compared native;
black locust ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0182526
Abstract: Objective The aim of this paper is to empirically evaluate whether widening educational inequalities in mortality are related to the substantive shifts that have occurred in the educational distribution. Materials and methods Data on education…
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Keywords:
inequalities mortality;
mortality;
educational expansion;
european populations ... See more keywords
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Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.833190
Abstract: Humans have a great diversity in phenotypes, influenced by genetic, environmental, nutritional, cultural, and social factors. Understanding the historical trends of physiological traits can shed light on human physiology, as well as elucidate the factors…
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Keywords:
european populations;
trajectories complex;
traits european;
populations modern ... See more keywords
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Published in 2020 at "Genes"
DOI: 10.3390/genes11111275
Abstract: Agranulocytosis is a rare yet severe idiosyncratic adverse drug reaction to metamizole, an analgesic widely used in countries such as Switzerland and Germany. Notably, an underlying mechanism has not yet been fully elucidated and no…
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Keywords:
genome wide;
induced agranulocytosis;
metamizole induced;
association ... See more keywords