Chemical constituents and synergistic anti-gout studies on Eurycoma longifolia and potential mechanisms evaluation based on systemic analysis approach.
Sign Up to like & getrecommendations! Published in 2019 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2019.103302
Abstract: 37 compounds mainly including triterpenoids with the quassinoid skeleton and β-carboline alkaloids have been isolated from the roots of Eurycoma longifolia Jack (EL), which has been used as traditional medicine for a long history. It… read more here.
Keywords: analysis; signaling pathway; constituents synergistic; chemical constituents ... See more keywords
Eurycoma longifolia, a promising suppressor of RANKL-induced differentiation and activation of osteoclasts: An in vitro mechanistic evaluation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Ayurveda and Integrative Medicine"
DOI: 10.1016/j.jaim.2017.07.014
Abstract: Background Eurycoma longifolia (E. longifolia) has gained remarkable recognition due to its promising efficacy of stimulating bone formation in androgen-deficient osteoporosis. Numerous in vivo studies have explored the effects of E. longifolia on osteoporosis; however,… read more here.
Keywords: rankl induced; differentiation; eurycoma longifolia; activity ... See more keywords
Evaluating the in Vitro Efficacy of Quassinoids from Eurycoma longifolia and Eurycoma harmandiana against Common Cold Human Coronavirus OC43 and SARS-CoV-2 Using In-Cell Enzyme-Linked Immunosorbent Assay.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.2c00736
Abstract: Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, has become a pandemic and public health crisis. SARS-CoV-2 and the seasonal common cold coronavirus (HCoV-OC43) belong to the beta genus of human… read more here.
Keywords: oc43 sars; common cold; coronavirus; eurycoma longifolia ... See more keywords
Structural Characterization and Immunomodulatory Activity of a Polysaccharide from Eurycoma longifolia.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.8b00238
Abstract: A polysaccharide, Ali-1, was isolated from the roots of Eurycoma longifolia, a popular traditional medicinal herb in Malaysia. The structure of Ali-1 was characterized by monosaccharide, methylation, and NMR data analyses. The average molecular weight… read more here.
Keywords: acid; residues linked; characterization immunomodulatory; immunomodulatory activity ... See more keywords
A Multifaceted Review of Eurycoma longifolia Nutraceutical Bioactives: Production, Extraction, and Analysis in Drugs and Biofluids
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c06340
Abstract: Eurycoma longifolia Jack (known as Tongkat Ali) is a popular traditional herbal medicine, native to southeast Asia, that is well-known for its aphrodisiac as well as several other effects. Mostly, the root extract of E.… read more here.
Keywords: production; medicine; extraction; eurycoma longifolia ... See more keywords
A Systematic Review on Antimicrobial and Antiparasitic Activity of Eurycoma longifolia Jack (Tongkat Ali)
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/4999797
Abstract: Eurycoma longifolia or Tongkat Ali (family: Simaroubaceae) has the potential to be utilised as an antimicrobial and antiparasitic agent that correlated with its traditional use to treat jaundice, malaria, antiseptic agent, and many more. This… read more here.
Keywords: antimicrobial antiparasitic; antiparasitic activity; review; eurycoma longifolia ... See more keywords
Hairy Root Cultures of Eurycoma longifolia and Production of Anti-inflammatory 9-Methoxycanthin-6-one
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DOI: 10.1177/1934578x1801300507
Abstract: The content of bioactive alkaloid 9-methoxycanthin-6-one in the roots of Eurycoma longifolia is rather small. In the current study, a high yield of 9-methoxycanthin-6-one was obtained from transgenic hairy roots (1.139 ± 0.20% dry weight,… read more here.
Keywords: production; inflammatory; methoxycanthin one; hairy root ... See more keywords
Phenolic-rich extracts of Eurycoma longifolia and Cylicodiscus gabunensis inhibit enzymes responsible for the development of erectile dysfunction and are antioxidants
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Basic and Clinical Physiology and Pharmacology"
DOI: 10.1515/jbcpp-2017-0160
Abstract: Abstract Background: Herbs have been used from ages to manage male sexual dysfunction. Hence, this study sought to investigate the effects of Eurycoma longifolia (EL) and Cylicodiscus gabunensis (CG) stem bark extracts on some enzymes… read more here.
Keywords: dysfunction; erectile dysfunction; longifolia cylicodiscus; cylicodiscus gabunensis ... See more keywords
HIGH-FREQUENCY INDUCTION OF MULTIPLE SHOOTS AND PLANT REGENERATION FROM COTYLEDONARY NODE EXPLANTS OF TONGKAT ALI (EURYCOMA LONGIFOLIA JACK)
Sign Up to like & getrecommendations! Published in 2020 at "Applied Ecology and Environmental Research"
DOI: 10.15666/aeer/1805_63216333
Abstract: Eurycoma longifolia Jack is traditionally used as an aphrodisiac and health supplement for various diseases. Due to its potential commercial value as a plantation crop as well as to conserve its germplasm, it is necessary… read more here.
Keywords: regeneration; longifolia jack; node explants; cotyledonary node ... See more keywords
Supplementation with Eurycoma longifolia Extract Modulates Diurnal Body Temperature Fluctuation and Sleep Rhythm in Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.68.342
Abstract: Eurycoma longifolia (Tongkat Ali; TA) is a traditional medicinal herb, commonly known as Malaysian ginseng. The root tea has been traditionally applied to treat fevers, aches, sexual dysfunction and other ailments. We evaluated the effects… read more here.
Keywords: extract; eurycoma longifolia; body temperature; supplementation ... See more keywords
How Internet Websites Portray Herbal Vitality Products Containing Eurycoma longifolia Jack: An Evaluation of the Quality and Risks of Online Information
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191911853
Abstract: Background: Tongkat Ali (TA) or Eurycoma longifolia is a herbal medicine (HM) plant traditionally used to treat sexual dysfunction and enhance libido in men. Websites containing information about HM are abundant. However, studies have shown… read more here.
Keywords: information; quality; quality risks; eurycoma longifolia ... See more keywords