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   Articles with "ev71 replication" as a keyword



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Harmine, a small molecule derived from natural sources, inhibits enterovirus 71 replication by targeting NF‐&kgr;B pathway

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recommendations! Published in 2018 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2018.04.050

Abstract: ABSTRACT Enterovirus 71 (EV71) infection of young children can cause neurological manifestations, which is mainly responsible for the fatality. Although a vaccine is recently available for preventing enterovirus 71 infection, its efficacy remains to be… read more here.

Keywords: ev71 infection; replication; ev71 replication; harmine ... See more keywords
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N-Acetyltransferase 8 Promotes Viral Replication by Increasing the Stability of Enterovirus 71 Nonstructural Proteins

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recommendations! Published in 2022 at "Journal of Virology"

DOI: 10.1128/jvi.00119-22

Abstract: EV71 is one of the most common pathogens causing HFMD in young children, and some patients experience severe or fatal neurological consequences. To ensure efficient replication, the virus must hijack multiple host factors for its… read more here.

Keywords: ev71 replication; ev71 infection; acetyltransferase; infection ... See more keywords
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TRAF3IP3 Is Cleaved by EV71 3C Protease and Exhibits Antiviral Activity

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recommendations! Published in 2022 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.914971

Abstract: Enterovirus 71 (EV71) is one of the major pathogens of hand, foot, and mouth disease, which poses a major risk to public health and infant safety. 3C protease (3Cpro), a non-structural protein of EV71, promotes… read more here.

Keywords: protease; traf3ip3; 3cpro cleavage; ev71 replication ... See more keywords
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Berberine prevents lethal EV71 neurological infection in newborn mice

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1027566

Abstract: Enterovirus 71 (EV71) is the major pathogen causing fatal neurological complications of hand, foot, and mouth disease (HFMD) in young children. Currently no effective antiviral therapy is available. In the present study, we found that… read more here.

Keywords: lethal ev71; ev71 replication; prevents lethal; infection ... See more keywords
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Honeysuckle Aqueous Extracts Induced let-7a Suppress EV71 Replication and Pathogenesis In Vitro and In Vivo and Is Predicted to Inhibit SARS-CoV-2

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recommendations! Published in 2021 at "Viruses"

DOI: 10.3390/v13020308

Abstract: Honeysuckle (Lonicera japonica Thunb) is a traditional Chinese medicine (TCM) with an antipathogenic activity. MicroRNAs (miRNAs) are small non-coding RNA molecules that are ubiquitously expressed in cells. Endogenous miRNA may function as an innate response… read more here.

Keywords: vitro vivo; sars cov; ev71 replication; expression ... See more keywords