Articles with "evaluating exarafenib" as a keyword



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Abstract CT032: Trials in progress: a global phase 1/1b clinical trial evaluating exarafenib (KIN-2787), a highly selective pan-RAF inhibitor, in adult patients with BRAF-altered solid tumors and NRAS mutant melanoma

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-ct032

Abstract: Background: Patients with cancers driven by BRAF Class II (C II) or C III alterations and/or NRAS mutations are unlikely to benefit from approved BRAF-targeted therapies and have few other treatment options. Exarafenib is a… read more here.

Keywords: raf inhibitor; solid tumors; evaluating exarafenib; pan raf ... See more keywords