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Evaluating the Genotoxic and Cytotoxic Effects of Thymidine Analogs, 5-Ethynyl-2′-Deoxyuridine and 5-Bromo-2′-Deoxyurdine to Mammalian Cells

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Published in 2020 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms21186631

Abstract: BrdU (bromodeoxyuridine) and EdU (ethynyldeoxyuridine) have been largely utilized as the means of monitoring DNA replication and cellular division. Although BrdU induces gene and chromosomal mutations and induces sensitization to photons, EdU‘s effects have not… read more here.

Keywords: evaluating genotoxic; cytotoxic effects; genotoxic cytotoxic; cytotoxic ... See more keywords