Evaluation of 99mTc-CN5DG as a broad-spectrum SPECT probe for tumor imaging
Sign Up to like & getrecommendations! Published in 2020 at "Translational Oncology"
DOI: 10.1016/j.tranon.2020.100966
Abstract: Highlights • 99mTc-CN5DG exhibited high tumor uptake, tumor/muscle and tumor/blood ratios in different kinds of tumor models.• 99mTc-CN5DG was stable in blood and tumors in vivo and rapidly cleared from blood.• SPECT/CT images in four… read more here.
Keywords: evaluation 99mtc; tumor; spect; cn5dg broad ... See more keywords
Synthesis and Evaluation of 99mTc-Labeled FAP Inhibitors with Different Linkers for Imaging of Fibroblast Activation Proteins in Tumors.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.2c02062
Abstract: Fibroblast activation protein (FAP) is a potential target for tumor diagnosis and treatment due to its selective expression on cancer-associated fibroblasts (CAFs) in most solid tumor stroma. Two FAP inhibitor (FAPI) derived ligands (L1 and… read more here.
Keywords: fibroblast activation; 99mtc labeled; tumor; evaluation 99mtc ... See more keywords