Synthesis of cinnamils and quinoxalines and their biological evaluation as anticancer agents
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202100448
Abstract: We synthesized multiple cinnamils and quinoxalines to evaluate their anticancer activity. Cinnamils were used as precursors for quinoxalines via condensation with 1,2‐diaminobenzene. Among the 26 synthesized compounds reported in this article, we found that cinnamil… read more here.
Keywords: cinnamils quinoxalines; quinoxalines biological; biological evaluation; synthesis cinnamils ... See more keywords
Novel Sulfonamide–Triazine Hybrid Derivatives: Docking, Synthesis, and Biological Evaluation as Anticancer Agents
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.3c01273
Abstract: The biological benefits of trisubstituted 1,3,5-triazine derivatives include their ability to reduce inflammation and fight cancer. A unique series of sulfonamide–triazine hybrid molecules were produced chemically by synthesizing triazine derivatives utilizing the usual nucleophilic aromatic… read more here.
Keywords: triazine hybrid; evaluation anticancer; triazine derivatives; sulfonamide triazine ... See more keywords
Evaluation of the anticancer activity of sprout extract-loaded nanoemulsion of N. sativa against hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2019.1571641
Abstract: Abstract Nigella sativa L. belonging to Ranunculaceae family is an important medicinal spice which has been utilised to treat various chronic diseases. Lipid nanoemulsions containing oil from medicinal plants have shown to enhance drug dissolvability,… read more here.
Keywords: sprout extract; sativa; evaluation anticancer; anticancer activity ... See more keywords
Evaluation of Anticancer Activity of Zhubech, a New 5-FU Analog Liposomal Formulation, against Pancreatic Cancer
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24054288
Abstract: Pancreatic cancer is projected to be the second leading cause of cancer-related death by 2030 in the US. The benefits of the most common systemic therapy for various pancreatic cancers have been masked by high… read more here.
Keywords: zhubech; formulation; pancreatic cancer; evaluation anticancer ... See more keywords