Articles with "evaluation collection" as a keyword



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Synthesis and evaluation of a collection of purine-like C-nucleosides as antikinetoplastid agents.

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Published in 2020 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2020.113101

Abstract: The kinetoplastid parasites Trypanosoma brucei, Trypanosoma cruzi and Leishmania spp. are the causative agents of neglected tropical diseases with a serious burden in several parts of the world. These parasites are incapable of synthesizing purines… read more here.

Keywords: collection purine; antikinetoplastid agents; evaluation collection; synthesis evaluation ... See more keywords