In Vitro Evaluation of [3H]CPPC as a Tool Radioligand for CSF-1R.
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DOI: 10.1021/acschemneuro.0c00802
Abstract: Microglia play a role in several central nervous system (CNS) diseases and are a highly sought target for positron emission tomography (PET) imaging and therapeutic intervention. 5-Cyano-N-(4-(4-[11C]methylpiperazin-1-yl)-2-(piperidin-1-yl)phenyl)furan-2-carboxamide ([11C]CPPC) is a radiopharmaceutical designed to selectively target… read more here.
Keywords: radioligand; evaluation cppc; tool; csf ... See more keywords