Evaluation of dual p16/Ki‐67 immunostaining on anal cytology specimens
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DOI: 10.1002/dc.25332
Abstract: Dual immunostaining for p16/Ki67 is FDA‐approved for use on liquid‐based cervical cytology specimens; however, the utility of dual staining in anal cytology especially for ASCUS risk stratification is not well established. read more here.
Keywords: evaluation dual; cytology specimens; dual p16; cytology ... See more keywords
Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
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DOI: 10.1016/j.ejmech.2020.112338
Abstract: Histone modifying proteins, specifically histone deacetylases (HDACs) and bromodomains, have emerged as novel promising targets for anticancer therapy. In the current work, based on available crystal structures and docking studies, we designed dual inhibitors of… read more here.
Keywords: design synthesis; evaluation dual; biological evaluation; dual targeting ... See more keywords