Synthesis and biological evaluation of fluorine substituted pyrazolo[4,3-e][1,2,4]triazines as purine analogues
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DOI: 10.1016/j.jscs.2016.11.004
Abstract: Abstract Some more new fluorine substituted pyrazolo[4,3-e][1,2,4]triazine derivatives (2 – 5) , 7 , 10 , 14 , 17 have been synthesized derived from hydrazinolysis of N-acyl/aroyl/dithioic formamido-2,3-dimethyl-1-phenyl-pyrazolo-5-ones which are obtained from 4-aminoantipyrine 1 .… read more here.
Keywords: fluorine substituted; biological evaluation; evaluation fluorine; substituted pyrazolo ... See more keywords
Design, synthesis and antiproliferative activity evaluation of fluorine-containing chalcone derivatives
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2020.1848627
Abstract: Abstract A series of new chalcones containing fluoro atom at B ring have been designed, synthesized, and evaluated to be antiproliferative activity against a panel of human tumor cell lines. Some of the analogs (8,… read more here.
Keywords: activity evaluation; synthesis antiproliferative; design synthesis; activity ... See more keywords