Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates
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DOI: 10.4110/in.2022.22.e28
Abstract: The 26S proteasome irreversibly hydrolyzes polyubiquitylated substrates to maintain protein homeostasis; it also regulates immune responses by generating antigenic peptides. An alternative form of the 26S proteasome is the immunoproteasome, which contains substituted catalytic subunits… read more here.
Keywords: immunoproteasome; fluorogenic peptide; peptide substrates; activity ... See more keywords