Evaluation of Xa inhibitors as potential inhibitors of the SARS-CoV-2 Mpro protease
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DOI: 10.1371/journal.pone.0262482
Abstract: Based on previous large-scale in silico screening several factor Xa inhibitors were proposed to potentially inhibit SARS-CoV-2 Mpro. In addition to their known anticoagulants activity this potential inhibition could have an additional therapeutic effect on… read more here.
Keywords: evaluation inhibitors; potential inhibitors; inhibitors potential; inhibitors sars ... See more keywords
Identification and Evaluation of Inhibitors of Lipase from Malassezia restricta using Virtual High-Throughput Screening and Molecular Dynamics Studies
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DOI: 10.3390/ijms20040884
Abstract: Recent studies revealed the role of lipase in the pathogenicity of Malassezia restricta in dandruff and seborrheic dermatitis (D/SD). The lipase from M. restricta (Mrlip1) is considered a potential target for dandruff therapy. In this… read more here.
Keywords: identification evaluation; evaluation inhibitors; mrlip1; malassezia restricta ... See more keywords