Synthesis and Biological Evaluation of a Library of Sulfonamide Analogs of Memantine to Target Glioblastoma.
Sign Up to like & getrecommendations! Published in 2023 at "ChemMedChem"
DOI: 10.1002/cmdc.202300134
Abstract: A library of 34 lipophilic sulfonamides based upon the memantine core has been synthesized to identify potential drug candidates to cross the blood-brain barrier and target glioblastoma. The library was screened for in vitro activity… read more here.
Keywords: synthesis biological; target glioblastoma; biological evaluation; evaluation library ... See more keywords
Evaluation of a library of loxP variants with a wide range of recombination efficiencies by Cre
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0276657
Abstract: Sparse labeling of individual cells is an important approach in neuroscience and many other fields of research. Various methods have been developed to sparsely label only a small population of cells; however, there is no… read more here.
Keywords: loxp variants; efficiencies cre; library loxp; evaluation library ... See more keywords