Evaluation on the Metabolic Activity of Two Carboxylesterase Isozymes in Mouse Liver Microsomes by a LC-MS/MS Method.
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DOI: 10.1093/chromsci/bmac105
Abstract: An applicable method for the precise measurement of major carboxylesterase (CESs) activity in liver still limited. Clopidogrel and irinotecan are specific substrates for CES1 and CES2, respectively. Clopidogrel is metabolized to the inactive metabolite clopidogrel… read more here.
Keywords: evaluation metabolic; mouse liver; liver microsomes; metabolic activity ... See more keywords