Discovery, Optimization, and Evaluation of Non-Nucleoside SARS-CoV-2 NSP14 Inhibitors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.5c01155
Abstract: We recently reported the discovery of TDI-015051, a first-in-class small-molecule inhibitor of the SARS-CoV-2 guanine-N7 methyltransferase nonstructural protein 14 (NSP14). NSP14 plays a critical role in viral RNA cap synthesis and its inhibition represents a… read more here.
Keywords: sars cov; optimization evaluation; cov nsp14; non nucleoside ... See more keywords
Performance evaluation of a non-equilibrium model for low temperature grain drying and simulation of seasonal dryer operation
Sign Up to like & getrecommendations! Published in 2020 at "Drying Technology"
DOI: 10.1080/07373937.2020.1832511
Abstract: Low temperature, fixed bed grain drying was investigated as an alternative to high temperature drying. Drying data was collected in an on-farm bin drying system over three harvest seasons. A one-di... read more here.
Keywords: low temperature; temperature; evaluation non; performance evaluation ... See more keywords
Evaluation of non-sexual, non-needlestick, non-occupational HIV post-exposure prophylaxis cases.
Sign Up to like & getrecommendations! Published in 2017 at "AIDS"
DOI: 10.1097/qad.0000000000001497
Abstract: 1. Menard A, Montagnac C, Solas C, et al. Neuropsychiatric adverse effects on dolutegravir: an emerging concern in Europe. AIDS 2017(in press). 2. Achra AC et al. Body mass index and the risk of serious… read more here.
Keywords: evaluation non; needlestick non; hiv; non needlestick ... See more keywords
Evaluation of a Non-Personalized Optopalatographic Device for Prospective Use in Functional Post-Stroke Dysphagia Therapy
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Biomedical Engineering"
DOI: 10.1109/tbme.2021.3094415
Abstract: Objective: Stroke survivors commonly suffer from dysphagia, originating from oro-facial impairments which affect swallowing function. Functional therapy often employs tongue exercises that require the patient to perform short motion sequences. Evaluating the patient's performance on… read more here.
Keywords: therapy; non personalized; evaluation non; dysphagia therapy ... See more keywords
A systematic approach to CT evaluation of non-arthritic hip pain
Sign Up to like & getrecommendations! Published in 2022 at "EFORT Open Reviews"
DOI: 10.1530/eor-22-0051
Abstract: Bone morphology has been increasingly recognized as a significant variable in the evaluation of non-arthritic hip pain in young adults. Increased availability and use of multidetector CT in this patient population has contributed to better… read more here.
Keywords: non arthritic; arthritic hip; evaluation non; hip pain ... See more keywords
Quantitative and Qualitative Evaluation of Non-Metallic Inclusions in High-Silicon Steel after Hot Rolling
Sign Up to like & getrecommendations! Published in 2024 at "Archives of Metallurgy and Materials"
DOI: 10.24425/amm.2024.149103
Abstract: This paper presents an analysis of non-metallic inclusions occurring in high-silicon steels containing about 3% Si of terms of their type, volume fraction and morphology. The inclusions were divided into 3 main groups: oxides, sulfides,… read more here.
Keywords: high silicon; non metallic; evaluation non; metallic inclusions ... See more keywords