Evaluation of oxadiazole-N-phenylacetamide conjugates as VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative assessment, molecular docking, and dynamics studies.
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DOI: 10.1080/17568919.2025.2594968
Abstract: AIM A novel series of oxadiazole-based derivatives was designed and synthesized as vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors. METHOD The synthesized compounds were evaluated for their cytotoxic and VEGFR-2 inhibition activities. RESULTS Compound 11i… read more here.
Keywords: vegfr inhibitors; oxadiazole phenylacetamide; phenylacetamide conjugates; evaluation oxadiazole ... See more keywords