Evaluation of Pharmacokinetics, Biodistribution, and Antimalarial Efficacy of Artemether-Loaded Polymeric Nanorods.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00507
Abstract: Artemether oily injection is recommended for the treatment of severe malaria by the intramuscular route. The major limitations of the artemisinin combination therapy are erratic absorption from the injection site and high dosing frequency due… read more here.
Keywords: polymeric nanorods; artemether loaded; microscopy; pharmacokinetics biodistribution ... See more keywords
Re-evaluation of the pharmacokinetics of xylazine administered to Thoroughbred horses.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of veterinary pharmacology and therapeutics"
DOI: 10.1111/jvp.12820
Abstract: Xylazine is widely used worldwide as a short-acting sedative in general equine and racing practice. In the UK, although it has a legitimate use during training, equine anti-doping rules state it is a prohibited substance… read more here.
Keywords: evaluation pharmacokinetics; thoroughbred horses; pharmacokinetics xylazine; administered thoroughbred ... See more keywords
Abstract 4086: Preclinical evaluation of pharmacokinetics, pharmacodynamics and efficacy of the dual CD73-A2AR Inhibitors
Sign Up to like & getrecommendations! Published in 2019 at "Immunology"
DOI: 10.1158/1538-7445.am2019-4086
Abstract: As a potent immunosuppressor adenosine is essential for maintaining tissue homeostasis and preventing an overzealous immune response during inflammation and infection. However, adenosine generated within the tumor microenvironment by the action of ecto-nucleotidases including CD73… read more here.
Keywords: preclinical evaluation; cd73; cd73 a2ar; evaluation pharmacokinetics ... See more keywords