Preclinical evaluation and phase 1 study of the PI3Kα/δ inhibitor TQ‐B3525 in Chinese patients with advanced cancers
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DOI: 10.1002/cncr.35453
Abstract: Phosphatidylinositol 3‐kinase (PI3K) inhibitors transformed management of various malignancies. This study preclinically characterized TQ‐B3525 (dual PI3Kα/δ inhibitor) and assessed the recommended phase 2 dose (RP2D), safety, efficacy, and pharmacokinetics in relapsed or refractory (R/R) lymphoma… read more here.
Keywords: preclinical evaluation; evaluation phase; pi3k inhibitor; pi3k ... See more keywords
Thermal Performance Evaluation of Phase Change Material-Integrated Triple-Glazed Windows Under Korean Climatic Conditions
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DOI: 10.3390/en18215754
Abstract: Passive design strategies incorporating phase change materials (PCM) provide effective thermal energy storage, improve indoor comfort, and reduce building energy demand. This study aimed to evaluate the effectiveness of partially filled PCM glazing systems in… read more here.
Keywords: performance evaluation; thermal performance; evaluation phase; phase change ... See more keywords