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Synthesis and evaluation of potent yaku'amide A analogs

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Published in 2022 at "Chemical Science"

DOI: 10.1039/d1sc05992k

Abstract: Two full-length analogs of the anticancer peptide yaku'amide A (1a) and four partial structures have been synthesized. These analogs were identified by computational studies in which the three E- and Z-ΔIle residues of the natural… read more here.

Keywords: synthesis evaluation; amide analogs; synthesis; yaku amide ... See more keywords