Evaluation of a Radiolabeled Macrocyclic Peptide as Potential PET Imaging Probe for PD−L1
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DOI: 10.1002/cmdc.202200091
Abstract: The interaction between the immune checkpoint PD‐1 and PD−L1 promotes T‐cell deactivation and cancer proliferation. Therefore, immune checkpoint inhibition therapy, which relies on prior assessment of the target, has been widely used for many cancers.… read more here.
Keywords: peptide potential; radiolabeled macrocyclic; potential pet; macrocyclic peptide ... See more keywords
Preparation and evaluation of radiolabeled gliclazide parenteral nanoemulsion as a new tracer for pancreatic β-cells mass.
Sign Up to like & getrecommendations! Published in 2023 at "International journal of radiation biology"
DOI: 10.1080/09553002.2023.2204914
Abstract: Purpose: The present investigation aims to develop and evaluate a radiopharmaceutical for targeting and assessing β-cells mass based on gliclazide, an antidiabetic drug that specifically binds the sulfonylurea receptor unique to the β-cells of the… read more here.
Keywords: cells mass; gliclazide parenteral; radiolabeled gliclazide; preparation evaluation ... See more keywords
Evaluation of Radiolabeled Girentuximab In Vitro and In Vivo
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DOI: 10.3390/ph11040132
Abstract: Girentuximab (cG250) targets carbonic anhydrase IX (CAIX), a protein which is expressed on the surface of most renal cancer cells (RCCs). cG250 labeled with 177Lu has been used in clinical trials for radioimmunotherapy (RIT) of… read more here.
Keywords: evaluation radiolabeled; dota scn; cg250; vitro vivo ... See more keywords