Articles with "evaluation sc0245" as a keyword



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Preclinical evaluation of SC0245, a small molecule inhibitor of ATR kinase.

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Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.15_suppl.e15642

Abstract: e15642Background: The ataxia telangiectasia and Rad3-related (ATR) kinase is a member of the phosphoinositide 3-kinase related kinase (PIKK) family. ATR plays an important role in maintaining genom... read more here.

Keywords: preclinical evaluation; kinase; small molecule; atr kinase ... See more keywords