Synthesis, Biological Evaluation and in Silico Studies of Novel Urea/Thiourea Derivatives of Lenalidomide
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.70079
Abstract: Designing new compounds from existing chemotherapeutic drugs to enhance inhibitory effects on tumor cells while overcoming multidrug resistance is one of the important strategies for new drug discovery in medicinal chemistry. A new series of… read more here.
Keywords: thiourea derivatives; synthesis biological; biological evaluation; urea thiourea ... See more keywords
Design, Synthesis, Antimicrobial Evaluation and In Silico Studies of Novel Indole Clubbed Pyrazole Linked 1,2,3‐Triazole Derivatives
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DOI: 10.1002/jhet.70001
Abstract: A series of novel indole–pyrazole–triazole hybrids (6a–o) was synthesized using a copper(I)‐catalyzed azide‐alkyne cycloaddition (click chemistry) under microwave irradiation. The target compounds were obtained in good yields from readily available, low‐cost starting materials under simple… read more here.
Keywords: chemistry; design synthesis; antimicrobial evaluation; synthesis antimicrobial ... See more keywords
Synthesis, phytotoxic evaluation and in silico studies for the development of novel natural products-inspired herbicides
Sign Up to like & getrecommendations! Published in 2020 at "Biocatalysis and agricultural biotechnology"
DOI: 10.1016/j.bcab.2020.101559
Abstract: Abstract Natural products are viable sources for the design of new chemical entities that may have their activities improved by fast/inexpensive synthetic modifications of their substituents. Herein we report the synthesis of six analogs of… read more here.
Keywords: evaluation silico; natural products; synthesis phytotoxic; synthesis ... See more keywords