Design, synthesis, and biological evaluation of stable β6.3-Helices: Discovery of non-hemolytic antibacterial peptides.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.02.057
Abstract: Gramicidin A, a topical antibiotic made from alternating L and D amino acids, is characterized by its wide central pore; upon insertion into membranes, it forms channels that disrupts ion gradients. We present helical peptidomimetics… read more here.
Keywords: design synthesis; biological evaluation; evaluation stable; helices discovery ... See more keywords
Evaluation of Stable Doses of Warfarin in a Patient Cohort.
Sign Up to like & getrecommendations! Published in 2020 at "Drug research"
DOI: 10.1055/a-1228-5033
Abstract: BACKGROUND Definitions for stable dose of warfarin varies in the reported studies. International warfarin pharmacogenetic consortium (IWPC) algorithm was generated from the data based on these definitions. OBJECTIVE In the present study, we primarily evaluated… read more here.
Keywords: stable doses; definitions stable; warfarin patient; doses warfarin ... See more keywords