Synthesis and biological evaluation of sulfonamide‐based compounds as inhibitors of carbonic anhydrase from Vibrio cholerae
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DOI: 10.1002/ardp.202200070
Abstract: This study reports our continued efforts to identify inhibitors capable of targeting carbonic anhydrases (CAs) expressed in bacteria. Based on previously identified chemotypes, we designed and synthesized new analogs that were screened toward the α,… read more here.
Keywords: synthesis biological; evaluation sulfonamide; biological evaluation; vibrio cholerae ... See more keywords
Synthesis and evaluation of Sulfonamide-Thiazolidinone conjugates as promising anticancer agents via carbonic anhydrase inhibition.
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DOI: 10.36740/wlek/197183
Abstract: OBJECTIVE Aim: This study focuses on developing and evaluating five newly created compounds targeting carbonic anhydrase isoforms found in solid tumors. Our primary goal is to create exceptionally potent anti-cancer drugs. PATIENTS AND METHODS Materials… read more here.
Keywords: carbonic anhydrase; anhydrase; thiazolidinone; synthesis evaluation ... See more keywords