Evaluation of Thymidine Phosphorylase Inhibitors in Glioblastoma and Their Capacity for Temozolomide Potentiation.
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DOI: 10.1021/acschemneuro.1c00494
Abstract: A number of studies have shown high levels of thymidine phosphorylase (TP) expression in glioblastoma (GBM), with trace or undetectable TP levels in normal developed brain tissue. TP catalyzes the reversible phosphorolysis of thymidine to… read more here.
Keywords: thymidine phosphorylase; thymidine; inhibitors glioblastoma; evaluation thymidine ... See more keywords