Articles with "evaluation trisubstituted" as a keyword



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Synthesis and biological evaluation of 1,3,4-trisubstituted pyrazole analogues as anti-mycobacterial agents

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Published in 2017 at "Medicinal Chemistry Research"

DOI: 10.1007/s00044-017-1821-1

Abstract: A series of 1,3,4-trisubstituted pyrazole derivatives (3a–f), (4a–r), (5a–f) and (6a–f) have been synthesized and evaluated for their Mycobacterium tuberculosis (MTB) (H37Rv) inhibitory activity. The structures of newly synthesized compounds were characterized by IR, 1H… read more here.

Keywords: anti mycobacterial; trisubstituted pyrazole; biological evaluation; evaluation trisubstituted ... See more keywords