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Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113640
Abstract: Polysorbates and Poloxamer 188 constitute the most common surfactants used in biopharmaceutical formulations owing to their excellent protein-stabilizing properties and good safety profiles. In recent years, however, a vast number of reports concerning potential risk…
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Keywords:
scattering detection;
biopharmaceutical formulations;
polysorbate poloxamer;
evaporative light ... See more keywords
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Published in 2017 at "Polymer Testing"
DOI: 10.1016/j.polymertesting.2017.10.002
Abstract: Abstract A new evaporative light scattering detector (ELSD) for the analysis of polyolefins by high temperature gel permeation chromatography (GPC) was recently introduced by Agilent Technologies. For the first time, we investigated the possibility to…
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Keywords:
high temperature;
scattering detector;
detector;
evaporative light ... See more keywords
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Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00021
Abstract: Nanomedicines including lipid- and polymer-based nanoparticles and polymer-drug conjugates enable targeted drug delivery for the treatment of numerous diseases. Quantitative analysis of components in nanomedicines is routinely performed to characterize the products to ensure quality…
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Keywords:
evaporative light;
light scattering;
chromatographic quantitation;
simultaneous chromatographic ... See more keywords